By Car from the airport:

Take the National Road (green signs, directions to Heraklion / Rethymnon. Stay on the National Road, and you go always straight, passing the city of Heraklion on your right. Pass also Palaiokastron and its bridge, and 2 1/2 km after, on your right, you will see a sign "Villa Octo". This is exactly where you need to exit the National Road. The road is rural at the beginning (dirt) and after 200 meters is made of cement. Pass Villa Octo on your right, and follow the downhill road for 500 meters, which leads to the house (it is the last house). The entrance of the house is through a small private alley.